By undoing the changes in gene activity, which are actually brought about by everyday life, scientists have started to slow even reverse aging.
The scientists have tweaked genes which turn adult cells back into embryonic-like ones in mice. They have resonant success extending their lives.
The changes also involved the reversal of mouse and human cells in vitro. They actually extend the life of one mouse with an accelerated – aging condition. Furthermore, the cells successfully promoted recovery from an injury in the middle-aged mouse.
According to Juan Carlos Izpisua Belmonte, who is actually the research’s senior author and also an expert in gene expression at Salk, said:
“Aging is something like plastic which we can manipulate.”
The research is also continuing at the Salk Institute for further Biological Studies.
In their research, they have rejuvenated cells by briefly turning on 4 genes which can turn adult cells back into an embryonic-like state.
David Sinclair is a Harvard University geneticist and anti-aging researcher. He was also not involved in the study but is doing some similar work. He said:
“I really think that epigenetic reprogramming is the ultimate way for reversing aging.”
One molecular biologist at the University of Washington named Matt Kaeberlein, who also studies aging, but was not taking part in the work, actually suggests that it may be possible not just to slow aging but also to reverse it. He claims:
“That is really exciting – which means that even in elderly people, it may be possible to restore youthful function.”
The community of molecular biology is still buzzing and our life expectancies keep extending day by day.